Hello Tenno,
I have created this Guide mainly for newer People and because I was being asked many times how I gained my Mastery Rank so quickly. If you are interested in how to gain Mastery Rank quickly whilst grabbing some sweet loot keep reading!

Mastery Ranking is a method of tracking a player's relative progress of how much of the game's content they have experienced. Mastery points are earned by ranking up companions/weapons and Archwings/Warframes through Affinity. Points can also be earned by successfully completing Junctions and nodes on the Sol system.

Higher Mastery Ranks unlock a number of benefits:

• More weapons, Warframes and mods (especially Syndicate and Riven Mods)
  
• Increases daily trading limit
  
• Increases Extractor deployment limit
  
• Raises maximum Void Trace capacity by 50 per rank
  
• Raises the maximum daily bonus amount of Syndicate standing by Syndicates 1000 (Conclave is considered a Syndicate for the purposes of bonus standing); standing gained by doing syndicate missions or by turning-in medallions is unaffected by the daily cap.

You can view your own Mastery Progress and Rank by hovering the cursor over your Avatar on the top left corner of the UI; The player's and squad members' profiles and Mastery progress can also be viewed by clicking profile under their equipment tab; others in chat or communications by selecting their name and clicking "Profile".

Below are the ways you can gain Mastery Points:

Bringing up the ranks of Weapons, Sentinel weapons and Archwing weapons earn 100 mastery points for each rank gained up to Rank 30 for a total of 3,000.

• Bringing up the ranks of Warframes, Companions and Archwings earn 200 mastery points for each rank gained up to Rank 30 for a total of 6,000.
  
• Clearing the main objective of a Mission node and extracting will grant an average of ~63 mastery points.
  
• Victory against the opponent frame in a Junction grants 1,000 mastery points.

Take note that each individual equipment will only grant its mastery points once per rank per variant — Polarization, selling a Rank 30 equipment and then purchasing & reusing it will NOT grant mastery points again, including in the event that a copy of an already max-ranked equipment is obtained and used. If an equipment below max rank is sold, then purchased and reused, only the ranks previously not gained will grant mastery points.

Variants of original weapons count as a different equipment for mastery ranking; Prime, Syndicates, Vandal, Wraith, Prisma and the Detron Mara.

Excess mastery points are not lost if a you reach the amount required to advance a rank — these will automatically fill the next mastery bar, displayed only once you have succeeded on the rank-up test.

As you may have seen in the previous explanations Mastery Rank is rather important. But is there a way to gain Mastery Rank and Loot at the same time? Yes there is.

Go to your Arsenal and make a seperate Loadout you can call it Mastery Rank or Farming, whatever you like. This way you wont mess up your normal loadout and can switch inbetween them whenever you start a mission.

Once you made your Mastery Rank Loadout, equip your newst unleveled Warframe (Re-leveling the same Warframe or Weapon via a Forma does not count!).

Now there is 2 Ways you can do this.

In every Weapon Slot equip a Weapon that is level 0 and you just freshly crafted or bought. Equip some Mods to it and you are done.

Note: Weapon that need re-leveling with a Forma do not count towards Mastery Rank.

Choose 1 of the level 0 Weapons you would like to level up first and the other 2 Weapons can be level 30.

This way you can use your High Level weapons and still put out lots of damage whilst leveling up one Weapon at a time.

Note: Weapon that need re-leveling with a Forma do not count towards Mastery Rank.

Once you have finished your Mastery Rank Loadout it is time to get some Loot. Depending on what Relics you need there will be a defense mission you are able to join for the first 10 Waves.

I personally recommend going to the Void - Taranis, 10 Waves will give you 2 Random Lith Relics. And due to the fact that this defense mission is mostly focused on a rather narrow Area, you easily can go on the corner of the Maps to recover health and shields if you need to.

Alternatively you can also go and do the sanctuary onslaught as its based on zones and waves of enemies to level up, however I recommend running this with atleast 1 more person, whether friend or random tenno.

If you are not bothered by Grinding, you can repeat this step as many times as you please and in no time you will have lots of relics in your pocket!

Sometimes there are Fissures on Defense / Excavation / Survival Missions. These are also very good for gaining Mastery Rank whilst cracking open some Relics and getting lots of Loot as you can do them almost infinitely.

If you are having a low level warframe and / or all weapons level 0 also, I recommend only the infinite Meso and Lith Relic Fissures.

Thank you very much for reading this Guide! If you enjoyed it or found it helpful please give it a thumbs up and a fave!

I would like to give a special thanks to the Community for correcting me on my previous mistake.

I also would like to mention that I have not written the entire Guide myself, the very beginning is simply copied from Warframe Wikia[warframe.wikia.com].

I mainly have decided to write this Guide as I see alot of new People asking questions on how to level up fast whilst also get some Loot or other questions that are simply found in the Wikia.

So I thought why not bring the Wikia to the Steam Guide for you to easily read it in your Overlay and also giving you my best solution to it.