If this is your first time playing guitar your fingers tips are going to go through a lot of changes. Electic Guitar string are very thin and will hurt, your not alone. The best thing to do is to play til it hurts, then putting your axe down. Your body will make your skin on your finger tips tougher buy noticing your banging the stuff out of them. It takes time though, so dont give up.
If you can afford two guitars I would suggest a classical guitar and an electic. The electic guitar is for using Rocksmith and rocking out. The classical is for playing when your fingers cant stand the steel strings. Classical guitar stings are usually make from nylon or gut with low tention metal string for the 1-3 strings.
Other thing you will need to look up are finger stretching. Im sure there are many videos to show how to do this. What your are trying to do is extend the reach of your fingers. I did this when I was a teenager righting the bus to and from school. You can do it while watching TV or other mindless times of the day. Take it slow don't overly hurt yourself.
When buying string for your electic you well want to go with a lighter gauge of strings and they will be underless tention. This will be easyer to press down and bend. Only draw back is that they break easier.
One thing I have notice that Rocksmith does not have is strumming patterns. There are quite a few to learn and learn in music. This will be another thing you should look up and learn. On that note look up picking too.

I didn't load any videos or pics as you can look these thing up as needed.

The Rocksmith cord is a very good quality, has good shielding and a break point to protect your axe and pc. I looked for other cords on the web but they looked very second class and a waste of money and time. The Rocksmith cord is pro made and happy to have it.

Rocksmith is a great aid to training your brain to play guitar.

I still have to look at my guitar now and then to get my fingerings correct. The trick is knowing your guitar/bass.

Take the time to practice your scales, all of them. Doing this will instill the postions of the frets and strings.

Play Scale Runner and Quick Pick daily

I know that doing your scales is not glamours by any means but its what all the solos are based off of.

To tell ya the truth im still learning my scales after years of playing, there are quite a few. I always found it difficult to find them pre internet. So Rocksmith is a blessing having them all in one place. Use it.

Positions are import to learn also. Basic information: 2 frets for index finger, middle two fingers one fret each and pinky gets 2 frets.

Each scale has their own shape, just matteres where you start them.

Chords are your next task.

There are like a billion ways to play the same chord, learn them all, muhahahaha. xD Just kinding. I have not found a plane posting of chords in Rocksmith, only thing that Rocksmith is missing. To understand chords more looking into music theory is the path you will need to travel, which may overwhelm you. It is not needed to learn to play guitar by any means.
Dawn of the chorded is pretty good at learning to quick change of chords. I have a poster and a book I used to learn chords. I found them extremely helpful. It takes a little while to get your fingers to learn the postions for chords. Getting rushed to me doesn't help in the beginning.

Riffs are the coolest!

Use the riff repeater to its fullest. Now to tell ya the truth I will not always get a 100% on the riff repeater. I get sick of playing it. What I get out of it is the rythem of the figure changes and to learn the section. Change the mastery to 100% before leave the riff, I don't always master it. I need to learn each section then put it together.

Go to event manager

The event

Songs

Rift repeater

I like Free speed. It allows you to get every note down. Only thing is that it gets kinda picky about bends. Have to try 2 or 3 times before it hears it. Can get kinda confusing to as to what note they want you to play. To change the mastry level; start the riff repeat and then hit esc and go to set mastery.

I'll go through each section that is different.

For me I don't know all the songs. This can add to the difficulties. You can listen to the song through Rocksmith(just practice and dont play) or on youtube. Knowing the changes and feel of the song always makes learning it easier.

I break off the events when they get old and go for the songs sections. Playing songs you enjoy is what we are all after. But expanding your ablities to play different styles is key to being a great guitarist, so try everything.

I play a bunch of different insturments a bit.

Learned piano basics with lessons in 3rd and 4th grade, I sucked and hated it.

Picked up Trombone in school in 5th grade and played through 7grade then pick up Tube for 8th grade.

Pick up Electric Bass guitar at the age of 15 and played with friends in the "band" xD losts of fun. Kept playing bass and still do on and off. Bought my first guitar at age 17, and fell in love. Started playing piano again soon after to learn chord and scale progressions. Used "Buggs Powers Chord Progessions"(great book if you can find it) Has all the standard chord progressions and music theory basics. I also used a chord book for guitar. Played with a some friends in a band, had a gig or two. But we were in school and well had prioities. Then I had kids and well they don't need to have good ears and not my substandard playing. xD I played now and then to keep the rust off the fingures. Kids are older now and I can focus a bit more on my playing. I don't think you want to see me on stage but I love playing and that is what matters.

Rock on!

my aplogies for my misspellings. ;)