Estimated Achievement Difficulty - 5/10
Offline Achievements - 17/21
Online Achievements - 4/21
Approximate Amount Of Time Required For 100% - 10-40 Hours. Varies greatly depending on any deck pack DLC unlocks you may have purchased.
Number Of Missable Achievements - None.
Difficulty Settings affecting achievements - No.
Bugged achievements - None.
Broken and Unobtainable Achievements - None.

Any issues, mistakes, spelling errors, grammatical horrors or just simple suggestions please post in the comments and I'll try to improve this guide as soon as possible. :)

The Spark
Win a game

Quite simply, win a game, any gamemode willt work.

Epic Conclusion
Defeat Tezzeret in the final single-player campaign battle

Tezzeret uses a Blue and Black Artifact deck and has some very strong card draw. Anything that's good against artifacts or has discard/damage based on cards in hand will do well against him. I recommend Liliana's mono-Black deck as it does well to turn some of his own strengths against him.

Dragon Slayer
Defeat Nicol Bolas in the single player campaign (Expansion 1)

Nicol Bolas uses a very powerful Black, Blue and Red based around powerful Dragon creatures and lots of direct damage/removal cards. Perhaps his most notable weakness is his reliance on three different mana colors which can sometimes result in an easy win for you if he gets some unlucky draws. A good strategy to employ is to simply flood him with weaker creatures and destroy him before he gets too many of his high powered creatures into play. I recommend Nissa Revane's Black and Green or any other similar deck that allows you to bring out a lot of creatures very fast.

Everything at Stake
Defeat Sorin Markov in the single-player campaign (Expansion 2)

Sorin Markov uses a mono-Black Vampire deck that is probably the strongest individual deck in the game. He has a good combination of cheap and strong creatures, buffs as well as some good healing abilities. Vampire Nocturnus and Vampire Nighthawk are the key creatures to watch out for and later in the match a Malakir Bloodwitch can end it all in a single swoop. I recommend using Chandra Ablaze's mono-Red deck and try to overwhelm him with direct damage, taking out his most important creatures when necessary. Decks that try to flood the enemy with smaller creatures can work as well but requires some lucky draws as his lifelink and deathtouch creatures as well as his many flying ones will make him come out on top in a slugfest more often than not.

Madness Suppressed
Defeat Sarkhan the Mad in the single-player campaign (Expansion 3)

Sarkhan the Mad uses a Black and Red deck based around extremely powerful endgame creatures. He has some good land-draw abilities and is someone that you should try and defeat before he gets his immensely powerful lategame creatures into play. For decks you should chose either something that focuses on direct damage, like Chandra Ablaze's mono-Red deck or something that focuses on early creature spam such as Nissa Revane's Black and Green deck. In any case your strategy should be to win the battle before he gets his 10/10 and similar creatures out on the field.

Magic: The Puzzling
Complete a challenge

Puzzling Master
Complete all challenges

Puzzling Grandmaster
Earn Puzzling Master and complete all Expansion 1 challenges

Standard Game Challenges:

A. Garruk Wildspeaker

1) Cast Angelic Blessing on Skyhunter Skirmisher.
2) Cast your second Angelic Blessing on Skyhunter Skirmisher.
3) Continue to attack phase and attack with your Skyhunter Skirmisher.

B. Elspeth Tiriel

1) Cast Threaten on Soul Warden.
2) Cast Raging Goblin.
3) Continue to attack phase and attack with all three of your creatures.

C. Garruk Wildspeaker

1) Activate Elvish Piper's ability to bring Roughshod Mentor into play.
2) Continue to attack phase and attack with your three Grizzly Bears.
3) Wait until Garruk has declared blockers.
4) Cast all three of your Giant Growth's on a Grizzly Bear that is not being blocked by a Wall of
Wood.

D. Chandra Nalaar

1) Cast Megrim.
2) Cast Ravenous Rats.
3) Continue to attack phase and attack with all.

E. Liliana Vess

1) Cast Elvish Eulogist.
2) Cast Elvish Warrior.
3) Cast Eyeblight's Ending, targeting the Nightmare.
4) Activate Immaculate Magistrate's ability on the Elven Riders. Make sure the first three steps have resolved before you do this.
5) Continue to attack phase and attack with the Elven Riders.

F. Chandra Nalaar

1) Cast Unsummon on Shivan Dragon.
2) Cast Unsummon on Shivan Hellkite.
3) Activate Prodigal Pyromancer's ability, targeting Chandra.
4) Continue to attack phase and attack with your Cloud Sprites and Phantom Warrior.

G. Nissa Revane

1) Cast Terror on the Elvish Champion.
2) Continue to attack phase and attack with everything.
3) When you are prompted to choose a target for Flameblast Dragon, select Creatures, then target your own Sprouting Thrinax.
4) Pay 3 out of 3 lands.

H. Liliana Vess

1) Cast Incinerate on Royal Assassin.
2) Cast Incinerate on Ravenous Rats.
3) Cast Pariah on Platinum Angel.
4) Activate Knight of the Skyward Eye's ability.
5) Play Sangrite Surge on Knight of the Skyward Eye.
6) Continue to attack phase and attack with Knight of the Skyward Eye and Mistmeadow Skulk.
7) After first strike damage has been dealt and Dread's ability has triggered, activate Brion Stoutarm's ability. Target yourself and sacrifice Knight of the Skyward Eye.

Expansion 1 Challenges:

A. Jace Beleren

1) Cast Etherium Sculptor.
2) Cast Onyx Goblet.
3) Cast Master of Etherium.
4) Cast Howling Mine.
5) Cast Loxodon Warhammer.
6) Cast Terror on the Wall of Air.
7) Activate Onyx Goblet's ability, targeting Jace.
8) Continue to attack phase and attack with everything.

B. Elspeth Tiriel

1) Cast Jagged Lightning. Target Angel of Mercy first, then your own Mudbutton
Torchrunner.
2) When Mudbutton Torchrunner dies, choose to deal 3 damage to Elspeth directly.
2) Cast Vengeful Firebrand.
3) Continue to attack phase and attack with Bramblewood Paragon and Vengeful Firebrand.

C. Liliana Vess

1) Cast a Plains.
2) Continue to attack phase and attack with Ambassador Laquatus.
3) Cast Condemn on Ambassador Laquatus.
4) During your second Main Phase, cast Kiss of the Amesha, targeting yourself.
5) Cast Wrath of God.
6) During your next turn, cast a Plains.
7) Cast Ambassador Laqautus.
8) Use Ambassador Laquatus's ability three times, targeting Liliana Vess.
9) Continue to your end phase.

Expansion 2 Challenges:

A. Garruk Wildspeaker

1) Cast the Swamp.
2) When asked to bring Bloodghast back from the graveyard, select no.
3) Select no once again.
4) Equip Vampire Nighthawk with Blade of the Bloodchief.
5) Cast Disfigure on one of the Ruthless Cullblades.
6) Cast your second Disfigure on the other one.
7) Cast Feast of Blood, targeting the Giant Spider.
8) Continue to combat phase and attack with your Vampire Nighthawk.

B. Garruk Wildspeaker

1) Cast Select Memory and exile every nonland card in your library from the game.
2) Cast Treasure Hunt.
3) Cast a Forest.
4) Cast Primal Frenzy on Maro.
5) Continue to attack phase and attack with Mako.

C. Nicol Bolas

1) Cast Evolving Wilds.
2) Sacrifice Evolving Wilds and choose an Island.
3) Cast Brainstorm. Place Dispeller's Capsule and Planar Cleansing on top of your library.
4) Cast Excommunicate on Phage the Untouchable.
5) Cast Polymorph on the Darksteel Colossus.

D. Tezzeret the Seeker

1) Continue until your turn is finished.
2) After Tezzeret's turn, continue until your turn is finished. When prompted to bring Lorthos, The Tidemaker onto the battlefield, select yes.
3) On your next turn, cast the Island.
4) Continue to combat phase and attack with Lorthos, the Tidemaker.
5) When prompted tap eight of Tezzeret's Islands.
6) When prompted about the additional cost, select yes.
7) Allow Lorthos, the Tidemaker to do combat damage.
8) Cast Unsummon, targeting the Platinum Angel.

E. Sarkhan Vol

1) Cast Eladamri's Call, putting Plated Geopede into your hand.
2) Activate Elvish Piper's ability, bringing Plated Geopede into play.
3) Cast Harrow. Sacrifice a tapped Plains and select two Forests.
4) Cast your second Harrow. Sacrifice a tapped Plains and select two Mountains.
5) Activate Khalni Heart Expedition's ability. Select two Plains.
6) Wait until the Plated Geopede's ability fully resolves, making him 13/13.
7) Cast Fling. Target players. Choose Sarkhan Vol, then sacrifice your Plated Geopede.

Expansion 3 Challenges:

A. Sorin Markov

1) Activate Triskelion's ability. Choose creatures and target Child of Night.
2) Activate Triskelion's ability. Choose creatures and target Blood Seeker.
3) Activate Triskelion's ability. Choose creatures and target Triskelion.
4) Cast Open the Vaults.
5) Equip Basilisk Collar to Triskelion.
6) Activate Triskelion's ability. Choose creatures and target Vampire Nocturnus.
7) Activate Triskelion's ability. Choose creatures and target Vampire Nighthawk.
8) Activate Triskelion's ability. Choose creatures and target Sengir Vampire.
9) Continue to attack phase and attack with everything.

B. Chandra Nalaar

1) Continue to attack phase and attack with everything. When prompted to deal one damage through Hissing Iguanar, select Chandra Nalaar.
2) During your second Main Phase, cast Mind Rot. Target yourself and discard Might of Oaks and Fireshrieker.
3) Cast Aggressive Urge on Zombie Goliath. When prompted to deal one damage through Hissing Iguanar, select Chandra Nalaar.

C. Jace Beleren

1) Cast Protean Hulk.
2) After Protean Hulk resolves, activate Bile Urchin's ability. When prompted, deal 1 damage to Jace Beleren.
3) Once prompted by Protean Hulk's effect upon hitting the graveyard, choose to bring all four creatures back into play.
4) Activate the ability on a Children of Korlis.
5) When prompted by Academy Rector's effect upon hitting the graveyard, put Necromancer's Covenant into play. Select yourself.
6) Use Evolving Wilds to search for a basic land card.

D. Ajani Goldmane

1) Activate Vampire Hounds, discarding Anarchist.
2) Activate Vampire Hounds, discarding Anger.
3) Activate Vampire Hounds, discarding Ravenous Baloth.
4) Cast Exhume and bring back Anarchist. When prompted through Anarchist entering play, return Patriarch's Bidding to your hand.
5) Cast Patriarch's Bidding. Select Beasts. When prompted through the two Goretusk Firebeasts entering play, choose Ajani Goldmane both times.
6) Activate Ravenous Baloth's ability, sacrificing Realm Razer.
7) Continue to attack phase and attack with everything. Using Baloth Woodcrasher, deal damage to declared blockers in any manner you wish.

E. Sorin Markov

1) Cast Hurricane, tapping 2 lands.
2) Cast Dragon's Claw.
3) Cast Act of Treason, targeting Abyssal Persecutor.
4) Continue to attack phase and attack with Abyssal Persecutor.

Defender of Foriys
Win a Two-Headed Giant game

Master of Artifice
Defeat Tezzeret & Sarkhan Vol in the cooperative campaign

To play the Two-Headed Giant campaign you need to plug in a secondary controller. If you don't have one you will need to borrow a Playstation/Xbox controller from a friend and use that.

A few things to note about these 2 vs. 2 matchups that is key to easy victories is the various effects two players on each side has on your abilities. For example, despite sharing the same pool of life anything that has an effect whenever you gain life only works when the life gain is direct at your avatar in the match. The most important thing to note about this is that a number of spells and abilities that deal damage have a double effet all of the sudden making certain cards immensly more powerful. Experiment with different decks and take note of spells that say "Each Opponent" in their description, those are the ones you want. I recommend Sorin Markov's mono-Black vampire deck as at least one of your choices for this campaign for it's high number of lifegiving and damagedealing abilities that double in 2 vs. 2 games.

Planeswalker
Unlock 100%

In order to unlock this achievement you need to complete all the single-player campaigns, complete all the Coop campaigns, finish all the challenges and unlock all the bonus cards for all decks. For easier card unlocks lower the difficulty, play custom duel, change advanced settings so your starting hand is 9 and opponents is 5 and play against Garruk Wildspeaker's mono-Green deck as it is one of the weakest decks in the hands of the AI. Garruk is also someone I advise using as your oppnent as much as possible except when otherwise stated.

Devastator
Deal 20 combat damage to a player in a single turn in a game

This is a fairly easy achievement and should come naturally through normal play. If for some reason it doesn't simply start a custom duel with a creature heavy deck and play defensively until you've built up a massive army and then attack and overwhelm your opponent. Pretty much any deck can be used for this.

Life Preserver
Increase your life total to 30 or more in single player, or 60 or more in Two-Headed Giant

Again, this will come to you through normal play but if it doesn't, playing with either Elspeth Tirel's mono-White deck or Sorin Markov's mono-Black deck should unlock this relatively quickly.

Overkill
Control creatures with a total power of 75 or more (Expansion 1)

Simplest way to unlock this is with Nissa Revane's Black and Green deck as it has a great many options for creating token creatures as well as */* strength creatures. Simply play defensively, building up your creature horde until it unlocks.

Salt in the Wound
An opponent's last permanent leaves the battlefield

Start a game with Jace Beleren's mono-Blue deck and restart the duel until you go first and have 2 Lands and a Boomerang in your starting hand. Then simply use the Boomerang on the first non-land card your opponent throws down. This strategy works more consistently against opponents that don't have many cards that cost one mana.

Overflowing Harvest
Put 8 lands onto the battlefield in one turn (Expansion 2)

Go to the Challenges menu and start the last challenge in Expansion 2 against Sarkhan Vol.

1) Cast Harrow, pick any tapped land, choose 2 Forests.
2) Cast Harrow, pick any tapped land, choose 1 Forest and any other mana.
3) Use the ability on your Khalni Heart Expedition and pick any two mana.
4) Cast Summoner's Pact and pick Eternal Witness.
5) Use the ability on your Elvish Piper and pick Eternal Witness, then pick Harrow.
6) Cast Harrow and pick any two mana.

Tsunami of Pain
Deal 12 combat damage to an opponent in a single attack with one blue creature

Use either Tezzeret the Seeker's Blue and Black Artifact deck to boost up a Master of Etherium or Jace Beleren's mono-Blue deck to boost up a Sphinx of Magosi. Remember that you have to deal 12 damage to the enemy player so it's recommended to either clear out any potentional enemy blockers first or to boost your chosen creature well past the required strength.

Spellslinger
Defeat someone who has earned the Spellslinger achievement

Simply play and defeat another player who has already unlocked this achievement. If you do not have any friends that can help you with this try looking on the steam forums or whichever gaming community you frequent.

Duels Master
Win 10 online matches

Simply play, and win, 10 games online. As the multiplayer component of this game is long dead you will most likely need to find a friend to help you boost this achievement. This also means you can skip the actual playing part as your opponent simply conceding counts as a win.

Duelist
Win 5 ranked matches

Same as above only it has to be done with ranked matches.

Last One Standing
Win a 3- or 4-player match (Expansion 2)

This requires you to find at least two other people to help you with but other than that it works exactly like the other online achievements.