The Binding of Isaac: Rebirth

The Binding of Isaac: Rebirth

26 ratings
Revalopod's Curated Selection of the Highest Quality Compatible Mods
By Revalopod
WARNING: many mods won't work until Repentogon is updated to support Repentance+
Until then, here's a mod collection that works on Repentance+

A categorised collection of mods that have been specifically picked based on the following requirements:
  1. Quality - these mods are up to a certain quality standard that I have personally judged and deemed good and nice and cool
  2. Balance - there won't be crazy OP mods or anything like that
  3. Vanilla styled - these mods are about improving and adding to the game, not changing the style of it, so no meme mods sorry
  4. Compatibility - these mods should work not only with the latest version of Repentance+, but also each other without major issues
  5. Co-op - these mods should work for co-op players as well

The reason why this is a guide and not a collection is so I can categorise mods into categories because I just like categorising things for some reason. Also I can write things about each one which I like to do.
Also I first started making this guide in 2021 but never got around to finishing it, but now that Repentance+ is out and there's a few new interesting mods, I decided I might as well update it and post it finally.
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Essential mods and functionality
These are mods that you should definitely get to ensure all other mods work correctly, or to add functionality to them.

REPENTOGON: Isaac Script Extender
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=3127536138
A script extender that is required by some mods. Also apparently helps with performance of mods.

Custom Stage API
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=1348031964
This mod is a prerequisite for several of the largest mods.

Mod Config Menu Pure
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2681875787
This mod allows you to adjust and customise many mods.

MiniMAPI: A Minimap API
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=1978904635
Adds new functionality and icons to the minimap. Not strictly required but a lot of mods recommend it.

External Item Descriptions
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=836319872
Highly recommended so you know what modded items will do, but not absolutely necessary.

Encyclopedia - An In-Game Wiki!
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2376005362
This mods basically acts as an in-game wiki so you can learn about the functionality of content mods or keep track of your progress on character mods.
Major expansion mods
These are mods that so so big and high quality that they could have been DLCs!

Improved & Reworked Foes
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2847697646
A massive overhaul to the quality and fun of dozens of enemies and bosses in the game. Insanely impressive mod that I can't recommend enough.

Fiend Folio: Reheated - 500 New Monsters!
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2851063440
Fiend Folio, a humungous mod that adds over 500 enemies and 23 bosses, and new minibiomes to floors like honeycomb rooms in the cellar. This mod adds so much variety it's insane. It might take a while to get used to everything and might seem a bit hard at first, but once you get used to it you'll love it to bits.

TBOI: Rekindled
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2761134241
A graphical overhaul of almost everything, made up of almost 300 mods combined into one to ensure less lag and utmost compatibility. This means you basically never have to install another visual improvement mod ever again, or worry about compatibility with certain mods. Also includes a handful of good gameplay tweaks. Highly recommend checking it out.

Revelations Ch. 2
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2880387531
A new path that has unique theming and mechanics. Adds 2 new floors, with a 3rd coming eventually. Also has over 80 enemies, 2 new characters, 61 new items and 17 bosses/minibosses.

Excelsior
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2701118263
A complete soundtrack replacement that revitalises the game—especially suited with Fiend Folio.
Sizeable content packs
Moderate sized content packs, not quite major expansions, but still great.

Tainted Treasure Rooms
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2818356312
A neat mod that adds a new kind of treasure room with tainted version of items.

God's Gambit
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=3290871743
Adds an entire new set of minibosses to replace the Sins in the Repentance alt path.

Boss Butch! (13 new bosses)
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=3297246061
Adds 13 well-designed and personality-filled bosses.

Crabby's Cretins
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=3014096448
Adds 30 new enemies, and lots of new rooms to encounter them in.

Reworked Foes Champions
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=3183902510
An addon for Improved & Reworked Foes that adds some new champions.

More Giant Props rooms! (Featuring Fiend and Folio!)
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2960638213
An addon to make giant props more common with Fiend Folio. (The base mod is included in Rekindled)
Minor content additions and game tweaks
They may be small, but they all add up to an overall improved game experience.

mars trigger
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2596349614
This mod singlehandedly made Mars one of my favourite items in the game. Now it's actually fun and intuitive to use. Also adds a hotkey for Divine Intervention!

Range fix for Bones & Sword
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=3033566163
Makes high range with melee not stupid. (included in TBOI: Rekindled)

Delirium Fix
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=3238785145
Fixes Delirium so that it's not as much of a cheating, unfair, telefragging, DPS check, objectively bad boss.

JamesB456's More Synergies Collection!
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2897486397
Adds more synergies to some items that were a bit lacking in that regard.

Neptunus Synergies
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2965292371
More synergies for Neptunus cus why not.

Akeldama Synergy
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2661109135
More synergies for Akeldama cus why not.

Ludovico Laser Fix
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=3374806352
Makes certain synergies work properly now.

ButtonBuff
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2542647370
A small change but it's nice and just makes sense.

The Trifecta Grants Godhead Tears
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2518147586
In the rare occasion you manage to get all 3 The Mind, Body and Soul, you get a bonus Godhead. This is just a neat interaction that makes sense.
QOL and convenience mods
These mods are ones I personally like to use but wouldn't really recommend using until you 100% the game as they can lower the difficulty a bit. They can make the game more enjoyable and fun though, so if you're struggling at the game, maybe give these a go to make your life a bit easier.

Faster Animations
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2499964071
Speeds up machines so you don't have to stand around for several minutes when you want to use all your money on a slot machine.

One Hit Poops And Fires
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=3249884026
When not in combat, fires and poops can be destroyed in a single hit. Just saves a bit of time.

Better Knife Pieces
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2875881571
After 100%ing the game, I don't always feel like doing the Knife Piece hunt segments again. This mod just skips that and gives you the pieces if you've already done it at least once before.

Watch out, laser!
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2887926286
Shows you a brief indicator before a laser attack so you don't get insta ouchied by a hitscan laser and become a sad

Coming Down!
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2878352867
Similar to the laser one but for stompy and jumpy enemies. This can be good because sometimes it can be very difficult to see the usual shadow indicators, especially on the Satan boss fight.

visible fortunes
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2874947730
Makes fortunes a bit less annoying if they pop up during gameplay which can happen with Fiend Folio.

cursed eye no tp
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2861800012
This mod may seem like cheating since it's removing the major gimmick and downside of the item. But Cursed Eye is just genuinely so bad, even with this mod, I find that Cursed Eye is just not worth picking up.

Item ban list
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=1372894129
Lets you add items to a blacklist so you never see them in the game again. I use this for a few things like Clicker, Gnawed Leaf and Plan C, all of which I never use so are wasted items.

NO CURSES
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=918170746
I personally find curses to be anti-fun and enjoy the game more without them.
Characters
These are mods that add a new character or 2 into the game, with some also featuring unlocks.

The Stranger
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2552647882
My favourite modded character, this is essentially many characters in one.

Shotty's Stranger Megapack
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2850135288
A huge expansion for the Stranger, basically adding another 450 characters to try!

Samael
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=897795840
Samael is a melee character, similar to the forgotten. What's great about this mod is seeing all the item synergies that interact with and change the look of the scythe, and also some new secret mechanics.

Bertran
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2297456697
Bertran is another melee character but is quite a bit more challenging. There's a few different attacks to learn and master, and a whole bunch of synergies.

The Deleted
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2681372884
The deleted
Untested/outdated
Mods that I've used previously but I haven't tested for Repentance+

IPECAC Community Mod
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=1925867065
IPECAC mod is one of the original large content expansions to the game and started as far back as 2016. This mod is still going strong and supports the latest versions of the game. This is also one of the most expansive mods, basically a free DLC and adds a new character, almost a hundred new items, a few thousand rooms, and dozens of new enemies and trinkets. This mod adds some very fun items and mechanics, and overall it's a high quality, well balanced and awesome mod that I definitely recommend.

Beggars Purgatory
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2178461317
This is a different kind of expansion, as instead of expanding the base game experience, it adds an entire new gamemode into the game with enough brand new mechanics and gameplay that it might as well be an entire new separate game! It's such a clever and well made mod and I can't recommend it enough.

Repentance Plus!
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2627014611
This mod fills in the remaining unlocks for the Tainted characters, giving them as many as their original counterparts. In total it adds 34 new items,17 new trinkets, 27 new cards, 5 new pills and 1 new chest. This makes Repentance feel even more feature complete and expansive and you won't want to be without this mod!

The Collections Collection
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2613077854
These collection mods add about a dozen themed features each, which all add up to a pretty decent amount of new and fun stuff that fits the game. They're basically Repentance booster packs! Note - several comments have indicated that these mods may make the game very laggy, so I'm keeping this in the Untested section for now.

Mei
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=842051906
While Mei was never a favourite of mine, Tainted Mei sure is! Their attack method is genius and perfectly fits the game. There's a great amount of synergies too which is really fun to see.

Job
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2567634705
Probably the mods feature complete character mod on the workshop right now, this adds a new playable character and tainted version, with 45 unlocks in total between the two.

Nemesis
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2501339433
This is one of the most unique modded characters I've seen, with a totally unique and fun attack mechanic. Instead of items acting as upgrades to your tears like any other character, you attacks are completely dependant on the flask you hold which are randomly generated and commonly dropped. Playing this character basically turns the game into a looter shooter! There's even a rarity system and you can swap between 2 equipped flasks.
Untested
Mods that look like they might be good but I haven't tried them to see if they adhere to my subjective standards.

Fall from Grace (Boiler and Grotto)
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2974704582
A 3rd set of floors for the Repentance alt path.

Last Judgement
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=3343815332
Adds some cut content to the game, particular the alt version of Corpse: Mortis! Also includes some improved spritework in the same style as Repentance's sprite reworks.

Retribution: 190 Items
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2881008017
Sort of like a companion mod to Fiend Folio, but instead of focusing on new enemies, it adds a plethora of new items—Over 190! Apparently isn't fully compatible with Repentance+ yet.

Deliverance
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=1762369129

The Binding of Isaac: Epiphany
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=3012430463

[RGON] Repentance Plus!
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2627014611

[RGON] Furtherance
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=3513706025

Lost And Forgotten
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=3440586497

Visual and audio mods
This section is pretty much irrelevant if you're using Rekindled. Because of that, I won't be updating this section anymore but will leave it up for now.
Some great visual/audio enhancement mods. Note that none of these should be used if you're already using TBOI: Rekindled as it already includes almost all of them anyway.

Improved Backdrops and Visuals
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2751333905
Improves the look of many backdrops. One of its best features is moss and stalactites in the caves, which adds so much to the atmosphere. See for yourself:


Doors for Improved Backdrops and Visuals
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2754801041
Some door resprites to go along.

Crawlspaces Rebuilt
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=3057349799
A visual overhaul to crawlspaces, compatible with Fiend Folio!

[Ultimate Sprite Collection]
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2513340607
Resprites dozens of items to make them a bit more special while still keeping the vanilla style and design rules.

Animated Items
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2570913695
90+ items are animated, which looks really cool.

Enhanced Boss Bars
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2635267643
A bunch of unique health bar sprites for bosses and new functionality such as multiple health bars when there's 2+ bosses

!very tinted folio rocks
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2861287097
A tinted rock resprite with a lot of effort put in so they don't stick out like a sore thumb while still looking unique and distinct enough so that you don't need to strain your eyes squinting at every rock to see a single grey pixel mark.

Boss Rush Wave Counter
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2492654252
Self explanatory, helps you know how much longer you have to endure in boss rush.

Better Explosions
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2879232973
Makes the explosion animation look much more smooth and satisfying, and improves the scorch marks too.

Unique Music for Cameo Bosses
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2535870360
Bosses that are cameos from other Edmund games (CHAD, Gish, etc) now have music taken from their game.

Tainted Names
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2488073636
The character selection screen will now show tainted character's unique names, with extra effort put into the font to make it fancy.

Mega Satan's Bling
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2488732246
Some slight improvements but it makes a difference.

Darker Hell
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2536976843
Makes it easier on the eyes and helps see details in the background better.

Fixed Pits V2
https://steamproxy-script.pipiskins.com/sharedfiles/filedetails/?id=2489184516
Fixes pits a bit but I don't know if it's still necessary.
Upcoming
Forgotten Fables
https://x.com/fablesteam
1 Comments
TinchoLC 4 Dec, 2024 @ 9:20pm 
THANKS