Folks, I've tried to make lots of wild builds, but hands down this one takes the cake.

Class Build:

Monk 7: Way of the open hand subclass for main source of damage and must-have passives, take Tavern Brawler feat at 4

Rogue 4: Thief subclass for extra bonus action and ASI feat for +2 STR

Barbarian 1: For unarmored defense based on CON, which gives +6 AC

Stats:

Base: STR 17, DEX 16, CON 8, INT 8, WIS 13, CHA 12

Improved: STR 24, DEX 18, CON 23, INT 8, WIS 13, CHA 12

Items:

Helmet: Horns of the Berserker (+2 to attack rolls, +2 Necrotic damage per unarmed attack)

Cloak: Cloak of Protection (+1 AC)

Chest: The Graceful Cloth (+2 DEX)

Gloves: Gloves of Soul Catching (1-10 Force damage per unarmed attack and heals 10 HP once a turn)

Boots: Bonespike Boots (+1 AC and saving throws, increases jump range, and gives Brutal Leap)

Amulet: Amulet of Greater Health (CON 23)

Ring 1: Crusher's Ring (+3m movement)

Ring 2: Ring of Free Action (bunch of utility)

Other key buffs:

Auntie Ethel's boon: +1 STR

Bite Araj Oblodra: +2 STR

Vampire ascendant: 1-10 Necrotic damage per unarmed attack

Mirror of loss +2 STR

Well...

Without anything, you land 4 attacks per turn. Haste and Ki points crank that up to 8 attacks per turn. Each one hits like a truck too. Roughly 280 avg damage per turn. Consistently.

This is not a glass cannon build, AC is sitting at 22, unarmored, mind you. With 23 CON and 10 healing per turn, dying even on tactician takes some effort. Crusher's Ring and unarmored movement from Monk combined lets Astarion move from target to target.

Have fun!