In order to get the Sprinter achievement you must complete the entire RE3 campaign in under 2 hours. I’ll be playing on Assisted difficulty so that enemies are weaker and we start with an Assault Rifle for Jill. Since Assisted mode also features Autosaves, I’d also recommend trying to use less than 5 manual saves from Typewriters so you can get an S rank and get the Sensational Work! Achievement in the same playthrough.

The timer only goes when you’re playing. If you pause the game the timer will stop and you’ll be able to see how much time has passed since you’ve started. If you think you’ve wasted too much time on a section I’d recommend reloading a save. If you happen to die, don’t select continue or the timer will keep going, instead reload a save. I’ll include what time I had at the beginning of each section so you have an idea of what time you should be aiming for. (I’m by no means a speedrunner but I had almost 45 minutes to spare at the end of my run so don't worry if you're a few minutes over my listed times). There’s also several items you can buy from the in-game store that should dramatically help with the run like extra inventory space upgrades and a rocket launcher with unlimited ammo. I won’t be using those in this guide, but feel free to use whichever items you’d like from the store.

You can also stack several other achievements in this playthrough like I Might Need These Later! By only using one healing item (noted in the walkthrough) since your health regenerates on Assisted and Minimalist which requires you to not open the item box once during your playthrough.

• Dodging will be vital in this playthrough. If you need help performing them, grab the S.T.A.R.S. Field Combat Manual from the item store.
  
• Try to pick up ammo and grenades whenever you see them, we’ll be skipping most optional areas so items may be scarce in certain parts. I'll also highlight certain items like grenades or flash grenades that I used to skip challenging parts.
  
• You don’t need to kill most of the zombies you’ll see throughout the playthrough. Most of them can be dodged or simply walked around.
  
• I’d strongly recommend playing through the game once or twice first so you’re familiar with the story and maps.

• Complete the Prologue by escaping Jill’s apartment and running through the Parking Garage. They're super linear so just focus on getting through them. Make your way to the Redstone Subway Station and begin your journey.
  
• After the cutscene introducing Mikhail, head outside the Redstone Subway Station.
  
• Take the Alleyway next to the Subway Station entrance through the gate and follow the alley out into the street.
  
• Head to the end of the street to trigger a cutscene. Turn around and head back the way you came. Another cutscene will play revealing a new path down some stairs.
  
• Take the stairs down to Moon’s Donut shop.
  
• Head through the donut shop and run into the Kite Rail Office on the right and grab The Fire Hose on the floor.

• Turn Around, head back outside, through the donut shop, up the stairs and left towards the fire, put the fire out using the fire hose on the hydrant and head to the Garage.
  
• Once inside, grab the Bolt Cutters from the wall.
  
• Head through the garage, down the alleyway. You’ll be attacked by some dogs as you make your way to the substation. In the Substation Office grab the Hip Pouch.

• Grab a Green Herb from the rack near the stairs for the spider attack later and the Lockpicking Kit in the box, left of the substation gate. Once you unlock the gate with the lockpicking kit, you’ll be attacked by a spider, use the green herb to remove the parasite effect. (This will be your only heal if you’re going for the I Might Need These Later! achievement)
  
• Run inside and flip the 4 substation switches.

• As soon as you enter the substation, follow the path until your first split in the path. Head left and run all the way down to the end, turn left and you'll find Switch 1.
  
• From Switch 1, turn around and walk forward, take the 2nd path on your right to find Switch 2.
  
• From Switch 2, head back to Switch 1, but this time take a left (the path to the right we skipped to get to switch 2) and run back towards the beginning. At the end of the path, turn right and run all the way down to the end, loop the corner and continue following the path. If you see a gate that leads to a ladder, do not enter it yet, keep following the path until you find Switch 3.
  
• Head back to the gate we walked past and climb the ladder. Follow the scaffolding and then climb down. Follow the path to the next fork then go right towards the Final Switch.
  
• After you flipped all 4 head back the way you came, two spiders will bust through the wall revealing a path to the beginning. Follow this path all the way down to Switch 1, take the final left turn at the end of the path and it will take you back to the beginning.

• Turn on the power and head back to the Subway Rail Office we got the fire hose from. You’ll have your first Nemesis chase here.
  
• Head to the room with the big monitor to set the subway path. The solution is:

RE - 01
FA - 02
RA - 03
SA - 02
FO - 01

• I’d also recommend heading into the other room in the office and grabbing the Shotgun from the cabinet using the Bolt Cutters. You’ll also fight your first Parasite Zombie while leaving this office. (the ones with the giant eyeball on their head). If the eyeball isn’t covered then a couple shots should bring it down. If it is covered, blast its legs and run past them.
  
• Run back to the Redstone Subway Station. You’ll have to outrun Nemesis again.
  
• Once you get back to the Redstone Subway Station, you’ll have a chase sequence from Nemesis. In the final room, use the vent on the wall to escape. After that you’ll be in the Sewers.

My Playthrough's Time: 18:02

• You’ll see a door to your right that will lead you to the Manager's Office Safe Room. Grab the sewer map off the wall.
  
• Our goal is to head to the Laboratory to grab the Battery Pack to escape the sewers. It’s a straight path from the Manager’s office to the Laboratory.
  
• You’ll also fight several Gammas (the weird frog creatures). The easiest way to defeat them is with a flame round from the grenade launcher. Otherwise use regular grenades or shoot when it opens its mouth to attack.
  
• Head to the office in the south to pick up the Grenade Launcher.
  
• You’ll be attacked by a Gamma on the way. You can find a hand grenade on the right hand side on the way to the office in some trash that should one-shot him. Otherwise just shoot his mouth when he opens it.

• From here, head back the way you came. When you reach the fork in the sewer, head left and make your way to the Laboratory.
  
  
  
  
• Once you have the Battery Pack, head back to the Management Office. You’ll fight 2 Gammas along the way. When you’re in the straight vertical hallway, you’ll see a yellow ladder to the left.

• Climb the ladder to the upper waterway.
  
• You’ll follow the curving path to a locked door requiring the Battery Pack to open. Once you open it, circle around and unlock the door so you can retrieve your Battery Pack. You’ll be attacked by more Gammas along the way.
  
• There’s a Security Office nearby that contains a Hip Pouch. If you have the time, open the door with the Battery Pack to grab the inventory upgrade. (DON’T FORGET TO GRAB THE BATTERY PACK ON YOUR WAY OUT!)
  
• From the security room, you’ll head straight down another hallway, make a right and head down a ladder to the beginning of the Sewers. Use the Battery Pack to open the door and head up the ladder to the next section.

My Current Runtime: 23:00

• This section is extremely linear. You’re going to be chased by Nemesis using a flamethrower up a building to the roof. Just follow the path and dodge the fire.
  
• Once on the roof you’ll start your first boss fight with Nemesis. This bossfight has two phases, the first one involves shooting the gas tank on his back until it explodes. Just run around the piles of wood to get behind him or shoot the electric generator when he’s near it to stun him. After the tank explodes you’ll start part two of the fight. For this part he’ll be chasing you with a melee weapon. Just shoot him in the head and chest until he goes down.

My Playthrough's Time: 26:01

• After the fight you’ll find yourself street level again. Follow the road until you reach a fire truck.

• Climb the truck and walk across the ladder. Once you jump down, head to Gun Shop Kendo. Take note of the gate right next to the gunshop.

• If you have the shotgun you’ll find a powerful mod on the shelf to the left as soon as you walk into the gunshop.
  
• Head to the back of the gunshop. You’ll have a short cutscene with Kendo. Once it’s over, grab the key hanging on the wall.
  
• Hack back outside to the front of the Gun Store. Use the key on the gate next to the Gun Shop and continue forward.
  
• Continue following the path ahead. You’ll be attacked by a few parasite zombies along the way. You’re going to be ambushed by Nemesis again, this time with a rocket launcher. The rocket launcher has a laser that will be trying to target you, if it turns red then he’s firing rockets at you. Simply sprint through this section and use dodges as necessary. After the chase you’ll end up back in Racoon City Uptown, except everything will be on fire. Head up the stairs before the Giant Charlie head starts rolling towards you. Turn around and run down the stairs and out of the direct path of it. Once it’s rolled by, run back up the stairs and turn right before going down the alley to Redstone Subway Station.
  
• After the chase, follow Carlos to the Subway. After a few cutscenes it’s time to start playing as Carlos.

My Playthrough's Time: 30:40

• You’ll start out in a makeshift graveyard outside the Racoon City Police Station. Head towards the entrance to the Police Station.
  
• You’ll be attacked by Zombie Brad. Take him down if you can and grab his keycard. It can be used to get extra items from the police cases.
  
• Your goal in this section is to get to the S.T.A.R.S office on the second floor.

• Starting in the Main Hall, head to the Reception room through the door that Tyrell opens.
  
• Follow the Hallway into the Operations Room. Inside the Operations Room, you’ll want to grab the Flash Grenade for later.
  
• Head through the door to the south into the room between the Operations room and the Records room. Take the door to the right outside into the hallway.
  
• If you feel like you’ve got plenty of time, head into The West office and you’ll find a small office inside with a safe. Inside you’ll find another Hip Pouch upgrade. The combination is Left 9, Right 15, Left 7.

• Head past the safety deposit box room and head north towards the staircase. Climb up both flights of stairs to the third floor. There’s a key laying on top of some boxes. There’s also a locker up here that can be opened with the code: DCM.
  
• Head back down to the first floor to the Safety Deposit Box room. You’ll be attacked by a Licker on the first floor. Use your flash grenade to stun him before shooting him in the head to defeat him. Once he’s defeated use the key to enter the Safety Deposit Box room.
  
• Once inside, use the keypad to type 104, 106 and 109. Then grab the Battery, Grenade and ammo.
  
• From here, head back to the staircase and run up to the second floor. Head into the locker room.
  
• There’s a locker in the bathroom you can open with the code CAP to grab another Flash Grenade
  
• Once inside. You’ll head left into a room with showers. You’ll see a cracked wall with a bomb on it. Grab the Detonator off the wall and combine it with the Battery. Stick the Detonator back on the wall to blow it up.
  
• Once you blow the wall a bunch of zombies will attack. Use the Grenade to kill most of them before heading out into the hallway.
  
• Use the Flash Grenade to stun the Licker then you can either kill it or run past it. The door to the S.T.A.R.S office is halfway down this hallway on the left hand side. Head inside.
  
• After a couple cutscenes inside the office, head back out the door you came in to complete this section.

My Playthrough's Time: 36:53

• We’ll be playing as Jill again. Run to the end of this Hallway and head left into the Safe Room. Grab the 4 Mine Rounds before heading out the door.
  
• The next section will have 2 large groups of zombies. Use a Mine Round or Grenade to quickly take them out or just run past them. After both groups you’ll find yourself outside next to a river.
  
• Run towards the covered bridge that crosses the river.
  
• After you cross the bridge you’ll find yourself in the 2nd Nemesis boss fight. Like the first one, this one has 2 phases. For the first one, just start shooting him with everything you’ve got. There’s a bunch of ammo around the perimeter of the courtyard. SAVE YOUR MINE ROUNDS FOR PART TWO! You’ll know part two has started when he starts running around the arena on the buildings. Shoot a mine round in front of him while he’s running on the walls and he’ll come crashing down. When he does you’ll see a worm-like creature pop out of his chest. This is what you’ll want to focus on shooting. Rinse and Repeat until he’s defeated. After another cutscene you’ll be playing Carlos again.

My Playthrough's Time: 41:19

• Your goal in the hospital is to grab a tape and a tape recorder to open Dr. Bards office located next to the Lab Reception room.

• You’ll leave the sickroom and find yourself in the lobby. Take the first set of doors to the right (not the ones that are chained) down the hallway to the Reception room. Push through here to the Courtyard.
  
• Once you’re in the Courtyard, head right and loop around the room to Lab Reception.
  
• Pick up the Tape Recorder on the reception table (or wait till after you have the Tape since this is the room you use it)
  
• From here, head down the hallway to Emergency Entrance, turn left and head to the other half of the courtyard.
  
• Once you enter, immediately turn right and head up the stairs to the 2nd floor.
  
• On the 2nd floor, head left to the Roof Room. Loop through this room and exit on the other end.
  
• From here, if you turn left you’ll find a map of the hospital on the wall and the Records Room on the left hand side which is a safe room. Otherwise head straight down the hallway towards the door to the Nurses Station. Instead of going through the door, turn right and follow this hallway till you see the broken window on the right hand side.

• Jump out the window. In the courtyard, grab the Assault Rifle Mod in the flower pot to the left. Head over to the bench and hop over it to the other half of the courtyard. Pick up the key on the ground.
  
• From here you’ll leave the courtyard. You should find yourself near the Lab Reception. You’re going to follow the same path again to the 2nd floor and through the Roof Room.
  
• As soon as you exit the Roof Room turn left and head down the hallway towards where we found the Map and the Records Room. Turn right around the corner and you’ll see another door on the left hand side to the Staff Room. There’s a locker room on the other end of the Staff Room that will require the key we found outside to open. Inside the Locker Room we’ll find a Staff ID inside one of the lockers.

• Time to leave the staff room, once you do you’ll be attacked by a Hunter Beta (the big guys with the long claws) I took them out using my Assault Rifle and mainly attacked their head. (Be careful, these enemies can kill you in one hit even on Assisted mode!)
  
• From here, head back to the door to the Roof room, turn left and take the hallway all the way to the end and enter the Nurses Station.
  
• There’s a safe in this room with another Assault Rifle Mod. The combination is: 9 left, then 3 right
  
• Once you enter the Nurses Station, take the door to your right and head down the hallway that loops around the Treatment room. At the end of the hallway you’ll be in the Linen Room. Turn right and you’ll see a door on the right to the Treatment Room.
  
• The treatment room will have 2 Hunter Betas inside. The easiest way to take them out is to open the door and throw a hand grenade inside to kill them both.
  
• Head to the otherside of the Treatment Room and grab the Tape. Now head all the way back to the Lab Reception room and combine the Tape and Tape Recorder. Use it to open the door to Dr. Bard’s Office.
  
• Once inside his office, run towards the big metal door and use his computer. After a short cutscene the door will open and you can grab the Vaccine.
  
• Run back to Jill in the Sickroom near the Lobby and Give her the Vaccine.

• Time for the Hospital Defense Section. Since this is Carlos’ last section don’t worry about saving ammo. This section is mainly about killing zombies and protecting the door to Jill. There’s two triggers for this section you’ll want to complete as quickly as possible.
  
• The first is after the lights go out. A Hunter Beta will bust through the chained door in the lobby. There’s a switch inside the room that will restore power.
  
• The second is after the zombies bust through the front door, there’s a military case with a detonator in it. Grab the detonator then put it back in the same box you got it from to activate the final timer. Once it explodes you’re in the home stretch.

My Playthrough's Time: 54:17

• Once you regain control of Jill, head out into the Lobby, after a quick cutscene, go through the hallway to the Reception, except this time, you’ll turn right and pick the lock to the Hospital Underground.

• Run through this section to the big elevator with the giant truck. Take it down to the underground warehouse.
  
• Off the elevator, there will be a scissor lift and a lever. Pull the lever to lower the lift, get on, then pull the lever on the lift. Once you finish riding the lift up you’ll see a door that will lead to a Safe Room. There's a Hip Pouch upgrade in here.
  
• From here you’ll leave the Safe Room and find yourself on a catwalk. Run across the catwalk and jump down on the right hand side. Run through the open door to the elevator and activate it. The power will go out and you’ll need to collect 3 fuses (If you grab them and put them in the fuse box in under 5 minutes you’ll get the Achievement Electric Slide)

• Starting at the elevator, head straight towards the control panel to the right to lower the lift. A Pale Zombie (The white ones with no eyes) will awaken. Either avoid him or take him down with a powerful weapon like the shotgun.
  
• Once the lift is lowered, jump on and raise it. Once raised you’ll find your First Fuse.
  
  
  
  
• From here, turn left and take the ladder down. You’ll be attacked by some zombie dogs here. Run straight down the path since the first two paths to your left will be blocked by debris. You’ll see the third path on your left that isn’t blocked. Turn left and follow this path till you see a gap on the shelves on the left hand side.
  
• Squeeze through the gap then continue forward. Take the stairs up. (don’t mess with the lift to the right) once at the top, turn right and cross the raised lift (it should already be raised).
  
• Once you cross it you’ll see another control panel. Pull the lever to raise it. Cross the raised lift to the platform on the left and take the ladder down.
  
• You’ll see the 2nd fuse, but when you get close to it a door to the left will open with a bunch of zombies on the other side. If you’re quick enough you can grab the fuse and run back to the ladder before they pour out. Another door with a Gamma will open on your way back. Either run past him or use a Flame Round to take him down.
  
• Climb the ladder and cross both raised lifts. You should see a door near the stairs you took up. Go through the door and you’ll be in a room with several zombies and a Pale Zombie. On the other side of the room go through the door on the left, climb down the ladder and grab the last fuse. Be careful because a Hunter Beta will jump out and attack.
  
• Go back up the ladder and in the room with the zombies. Once through the door, turn left and unlock the door. Go through it and you’ll be back in the Safe Room. Head through the double doors, cross the Catwalk, jump down. 3 Parasite Zombies will awaken on your way to the elevator, you can either take them down or dodge them. Put the 3 fuses in the fuse box next to the elevator and ride the elevator up. In the Surveillance Room interact with the computer, after another cutscene, it’s time for the final section!

My Playthrough's Time: 1:01:26

• After some cutscenes, you’ll find yourself in a hallway. Follow the path to the end of the hallway to the door with a green panel next to it. This is a Safe Room, and the main thing to grab here is the note about Employee Registration since it has a map of the facility.
  
• From here, exit the Safe Room and take the stairs to the left. At the top of the stairs, turn left and head down the hallway. You’ll see a door on the Left hand side of the hallway. This is the room you need to bring the vaccine ingredients to, but for now, head over to the computer monitor in the corner and grab the Override key.

• Leave this room and head back down the stairs. At the bottom of the stairs, go left and head down the hall till you see a door on the left with a red panel. Use the Override key on the door to open it.
  
• The next room will have a bunch of Pale Zombies, so you’ll need to use your stronger weapons on them. Once you enter the room, run up the stairs, past the Pale Zombie going down the stairs and follow the catwalk into Lab 1. Grab the Culture Sample from the machine.
  
• Turn around and head back down the stairs. Once at the bottom, turn around and head deeper in the room, past all the hanging black bags, there’s a door on the left that we’ll be going through.
  
• In the next room, you’ll see a set of stairs leading down. Take them down. You’ll see a locked door. To open it, head right and go around the room till you see a big red cylinder with a zombie. Push the cylinder in to open the door.
  
• Go through the newly unlocked door and run to the other side of the room. You’ll take an elevator up to a new floor.
  
• Follow the path on the left to the door on the left. A bunch of zombies will pour out of the room. After you take them out, head inside and grab the Liquid Sample. Combine it with the Culture Sample to get the Vaccine Base.
  
• Head back to the Safe House. On your way back you’ll be ambushed by a couple Hunter Betas.
  
• Once you make it to the Safe House. Take the set of stairs to the left of the Safe Room to the 2nd floor and go back to the room you got the Override Key from to use the Vaccine machine.

• Head to the machine next to the vats and use the vaccine sample, you’ll then need to adjust the machine’s settings. The solution is: Mid High Low.
  
• After a cutscene you’ll be on a catwalk. Head forward to the vent and another cutscene will play.
  
• After a short scene, you’ll now be in a Safe Room. Grab the ammo and get ready for another Nemesis fight. Once you’re ready, head out the door and run down the catwalk towards the stairs.

My Playthrough's Time: 1:08:22

• This fight is very similar to the 2nd fight with a few notable differences.
  
• For Phase 1, you just need to shoot him with everything you’ve got. Like before, hang on to some Mine Rounds for Phase 2.
  
• Phase 2 starts after a cutscene with Carlos plays. Nemesis will run around the walls of the arena and hide behind/on a vat. Once you find him either shoot the red squares to knock him down or hit him with a Mine Round. Once he falls down, the worm creature will pop out of his chest again. Shoot it as much as you can until you defeat him.
  
  
• One thing to note is that zombies will occasionally spawn in the arena. If you have the ammo just take them out, otherwise Nemesis will kill them when he’s running around the arena.
  
• After the bossfight, there will be a cutscene, after that run down the hall to the final Safe Room.
  
• Once you’re ready, it’s time for the final fight. Head out of the Safe Room and run down the hall to start the next fight

My Playthrough's Time: 1:12:05

• This fight is extremely straightforward. Start by turning around and using the massive machine and shoot Nemesis with the Rail Gun. You’ll now need to charge the gun again.
  
• To charge the gun, you’ll need to push 3 power cores back into place. But first you’ll need to stun Nemesis by shooting the red polyps that appear on his body. Once you’ve stunned him you should have time to push 1-2 core in. Once all the cores are pushed in, shoot Nemesis with the rail gun and kill him for good. Run through the hole that was once Nemesis and climb the yellow ladder to the right.
  
• The final step is easy. After you’ve skipped the cutscenes you just need to shoot Nikolai (and try not to hit Carlos). Congratulations, mission complete!

I finished my playthrough at: 1:15:27.



I still made several mistakes during my run, but the game is very forgiving with its time. Just focus on getting through the main story and don't waste time on optional areas.

I hope this guide helps you out, if so please leave a like!